Ochratoxin A 'in vitro' biosynthesis by the Aspergillus ochraceus E'G isolate

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Ochratoxin a „in Vitro" Biosynthesis by the Aspergillus Ochraceus E'g Isolate

This paper deals with the biosynthetic capacity for ochratoxin A (OTA) production by Aspergillus ochraceus E'G isolate derived from A. ochraceus CBS 108.08 strain, during 2007. Preliminary analysis of fungal potential for the production of OTA were performed according to the modified method of F i l t e n b o r g et al. (1983). Toxin production was tested in the following liquid media: (i) gluc...

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Ochratoxin production by the Aspergillus ochraceus group and Aspergillus alliaceus.

Ochratoxin A is a toxic and carcinogenic fungal secondary metabolite; its presence in foods is increasingly regulated. Various fungi are known to produce ochratoxins, but it is not known which species produce ochratoxins consistently and which species cause ochratoxin contamination of various crops. We isolated fungi in the Aspergillus ochraceus group (section Circumdati) and Aspergillus alliac...

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A Saccharomyces cerevisiae Wine Strain Inhibits Growth and Decreases Ochratoxin A Biosynthesis by Aspergillus carbonarius and Aspergillus ochraceus

The aim of this study was to select wine yeast strains as biocontrol agents against fungal contaminants responsible for the accumulation of ochratoxin A (OTA) in grape and wine and to dissect the mechanism of OTA detoxification by a Saccharomyces cerevisiae strain (DISAABA1182), which had previously been reported to reduce OTA in a synthetic must. All of the yeast strains tested displayed an a...

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Production of ochratoxin A by Aspergillus ochraceus in a semisynthetic medium.

Aspergillus ochraceus NRRL 3174 produced 29 mg of ochratoxin A per 100 ml of nutrient medium consisting of 4% sucrose and 2% yeast extract. Ochratoxin A was the sole metabolite present in the chloroform extracts of the growth medium. Trace amounts of ochratoxin B were produced in a 1% yeast medium, and a comparatively large amount of ochratoxin B was produced in media containing 16 and 32% sucr...

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Functional Characterization of New Polyketide Synthase Genes Involved in Ochratoxin A Biosynthesis in Aspergillus Ochraceus fc-1

Ochratoxin A (OTA), a potentially carcinogenic mycotoxin which contaminates grains, is produced by several Aspergillus species. A comparative sequence analysis of the OTA-producing Aspergillus ochraceus fc-1 strain and other Aspergillus species was performed. Two new OTA-related polyketide synthase (PKS) (AoOTApks) genes were identified. The predicted amino acid sequence of AoOTApks-1 displayed...

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ژورنال

عنوان ژورنال: Matica Srpska Journal for Natural Sciences

سال: 2009

ISSN: 0352-4906,2406-0828

DOI: 10.2298/zmspn0917069b